Overview
Shadowrun is a science fantasy tabletop role-playing game set in an alternate future in which cybernetics, magic and fantasy creatures co-exist. The game has gone through multiple variations and versions, since its first release in 1989, the latest "Sixth World" game system was published in 2019, by Catalyst Game Labs. It combines genres of cyberpunk, urban fantasy, and crime, with occasional elements of conspiracy, horror, and detective fiction.
The system it directly evolved from is
Shadowrun 5th Edition
Description
Shadowrun takes place several decades in the future (2050 in the first edition, currently 2088). The end of the Mesoamerican Long Count calendar ushered in the "Sixth World" with once-mythological beings (e.g. dragons) appearing and forms of magic suddenly emerging. Large numbers of humans have "Goblinized" into orks and trolls, while many human children are born as elves, dwarves, and even more exotic creatures. The Shadowrun world is cross-genre, incorporating elements of both cyberpunk and urban fantasy. Unlike in a purely cyberpunk game, in the Shadowrun world, magic exists and has "worked" since 2011.
System Overview & Key Features
The d6 Dice Pool
The core resolution engine uses a massive pool of six sided dice. To attempt a test, a player adds their relevant Attribute and Skill together, then rolls that many dice. Every 5 or 6 rolled counts as a "hit" and players need to roll a certain number of hits to succeed.
The Edge System
In the Sixth World edition, Edge is a fluid tactical resource. Instead of tracking dozens of tiny situational modifiers, characters earn Edge points during a fight by having a superior position, better gear, or catching the enemy off guard. These points are spent immediately for rerolls or special combat actions.
The Three Worlds
The game takes place across three distinct layers of reality. Physical combat happens in meatspace, hackers project their consciousness into the virtual reality of the Matrix, and mages project their spirits into the magical Astral Plane. A well balanced team must handle threats from all three directions at once.
Magic and Drain
Spellcasters do not use spell slots. Instead, they can cast spells as often as they like, but channeling arcane energy takes a physical toll. Every time a spell is cast, the mage must resist "Drain" which can cause severe stun or physical damage if they are not careful.
Additional links
shadowrunsixthworld.com 
https://shadowrunsixthworld.com - Official Shadowrun website
catalystgamelabs.com https://catalystgamelabs.com - Official Catalyst Game Labs website